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This is because these free radicals are highly reactive and they can travel throughout the body to pair up with electrons

Based on the relative GSH-BDA excretion rate of male rats (2.18% of the external dose), PDIs of smokers ranged from 0.13 to 2.70 g/kg bw/d, thus exceeding the maximum 95th exposure estimate of 1.22 g/kg bw/d in adults, as well as the maximum 95th exposure estimate of 1.82 g/kg bw/d in infants (EFSA 2017) (Table 4)